Cargando…
CCN3/NOV promotes metastasis and tumor progression via GPNMB-induced EGFR activation in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. TNBC patients typically exhibit unfavorable outcomes due to its rapid growth and metastatic potential. Here, we found overexpression of CCN3 in TNBC patients. We identified that CCN3 knockdown diminished cancer ste...
Autores principales: | Son, Seogho, Kim, Hyungjoo, Lim, Hogeun, Lee, Joo-hyung, Lee, Kyung-min, Shin, Incheol |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898537/ https://www.ncbi.nlm.nih.gov/pubmed/36737605 http://dx.doi.org/10.1038/s41419-023-05608-3 |
Ejemplares similares
-
Role of the CCN protein family in cancer
por: Kim, Hyungjoo, et al.
Publicado: (2018) -
Glut1 promotes cell proliferation, migration and invasion by regulating epidermal growth factor receptor and integrin signaling in triple-negative breast cancer cells
por: Oh, Sunhwa, et al.
Publicado: (2017) -
NOV story: the way to CCN3
por: Perbal, Bernard
Publicado: (2006) -
N‐glycosylated GPNMB ligand independently activates mutated EGFR signaling and promotes metastasis in NSCLC
por: Han, Chia‐Li, et al.
Publicado: (2021) -
Expression pattern and prognostic impact of glycoprotein non-metastatic B (GPNMB) in triple-negative breast cancer
por: Huang, Yu-Hsiang, et al.
Publicado: (2021)