Biomolecular condensate assembly of nArgBP2 tunes its functionality to manifest the structural plasticity of dendritic spines

nArgBP2, a candidate gene for intellectual disability, is a postsynaptic protein critical for dendritic spine development and morphogenesis, and its knockdown (KD) in developing neurons severely impairs spine-bearing excitatory synapse formation. Surprisingly, nArgBP2 KD in mature neurons did not ca...

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Detalles Bibliográficos
Autores principales: Cho, Eunji, Lee, Sang-Eun, Lee, Unghwi, Goh, Yuna, Jeong, Seonyoung, Choi, Junyoung, Jeong, Won-Ki, Chang, Sunghoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898538/
https://www.ncbi.nlm.nih.gov/pubmed/36599935
http://dx.doi.org/10.1038/s12276-022-00918-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898538/
https://www.ncbi.nlm.nih.gov/pubmed/36599935
http://dx.doi.org/10.1038/s12276-022-00918-6

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