Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus

Human cytomegalovirus (HCMV) frequently causes congenital infections, resulting in birth defects and developmental disorders. A vaccine is needed, but unavailable. We analyzed the potential of CMV mutants, lacking their STAT2 antagonists to serve as live attenuated vaccine viruses in mice. Infection...

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Detalles Bibliográficos
Autores principales: Le-Trilling, Vu Thuy Khanh, Jagnjić, Andreja, Brizić, Ilija, Eilbrecht, Mareike, Wohlgemuth, Kerstin, Rožmanić, Carmen, Herdman, Alan, Hoffmann, Katja, Westendorf, Astrid M., Hengel, Hartmut, Jonjić, Stipan, Trilling, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898546/
https://www.ncbi.nlm.nih.gov/pubmed/36737485
http://dx.doi.org/10.1038/s41541-023-00602-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898546/
https://www.ncbi.nlm.nih.gov/pubmed/36737485
http://dx.doi.org/10.1038/s41541-023-00602-4

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