Identification of disease-related aberrantly spliced transcripts in myeloma and strategies to target these alterations by RNA-based therapeutics

Novel drug discoveries have shifted the treatment paradigms of most hematological malignancies, including multiple myeloma (MM). However, this plasma cell malignancy remains incurable, and novel therapies are therefore urgently needed. Whole-genome transcriptome analyses in a large cohort of MM pati...

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Detalles Bibliográficos
Autores principales: Ogiya, Daisuke, Chyra, Zuzana, Verselis, Sigitas J., O’Keefe, Morgan, Cobb, Jacquelyn, Abiatari, Ivane, Talluri, Srikanth, Sithara, Anjana Anilkumar, Hideshima, Teru, Chu, Michael P., Hájek, Roman, Dorfman, David M., Pilarski, Linda M., Anderson, Kenneth C., Adamia, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898564/
https://www.ncbi.nlm.nih.gov/pubmed/36737429
http://dx.doi.org/10.1038/s41408-023-00791-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898564/
https://www.ncbi.nlm.nih.gov/pubmed/36737429
http://dx.doi.org/10.1038/s41408-023-00791-0

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