PRPF8 increases the aggressiveness of hepatocellular carcinoma by regulating FAK/AKT pathway via fibronectin 1 splicing

Hepatocellular carcinoma (HCC) pathogenesis is associated with alterations in splicing machinery components (spliceosome and splicing factors) and aberrant expression of oncogenic splice variants. We aimed to analyze the expression and potential role of the spliceosome component PRPF8 (pre-mRNA proc...

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Detalles Bibliográficos
Autores principales: López-Cánovas, Juan L., Hermán-Sánchez, Natalia, del Rio-Moreno, Mercedes, Fuentes-Fayos, Antonio C., Lara-López, Araceli, Sánchez-Frias, Marina E., Amado, Víctor, Ciria, Rubén, Briceño, Javier, de la Mata, Manuel, Castaño, Justo P., Rodriguez-Perálvarez, Manuel, Luque, Raúl M., Gahete, Manuel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898568/
https://www.ncbi.nlm.nih.gov/pubmed/36609600
http://dx.doi.org/10.1038/s12276-022-00917-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898568/
https://www.ncbi.nlm.nih.gov/pubmed/36609600
http://dx.doi.org/10.1038/s12276-022-00917-7

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