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Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects

BACKGROUND: The incidence of intervertebral disc degeneration (IVDD) is a common degenerative disease with inflammation, decreased autophagy, and progression of fibrosis as its possible pathogenesis. Physalin A (PA) is a widely studied anti-inflammatory drug. However, its therapeutic effects on IVDD...

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Detalles Bibliográficos
Autores principales: Lu, Rui, Xu, Haoran, Deng, Xiaofeng, Wang, Yingguang, He, Zhiyi, Xu, Shimeng, Liang, Shuang, Huang, Xiaojian, You, Hongbo, Guo, Fengjing, Cheng, Peng, Chen, An-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898579/
https://www.ncbi.nlm.nih.gov/pubmed/36788965
http://dx.doi.org/10.1016/j.jot.2023.01.001