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Estrogen receptor targeting with genistein radiolabeled Technetium-99(m) as radiotracer of breast cancer: Its optimization, characterization, and predicting stability constants by DFT calculation

OBJECTIVE: Genistein is an isoflavone molecule with a high affinity for estrogen receptors (ER), which could lead to the mechanism of selective estrogen receptor modulators (SERMs) in breast cancer. Genistein labeling with technetium-99(m) can be a new promising strategy for diagnostic breast cancer...

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Detalles Bibliográficos
Autores principales: Ramdhani, Danni, Listiani, Nita, Sriyani, Maula Eka, Maria W, Eva, Watabe, Hiroshi, Mustarichie, Resmi, Fitri Kusuma, Sri Agung, Janitra, Regaputra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898673/
https://www.ncbi.nlm.nih.gov/pubmed/36747562
http://dx.doi.org/10.1016/j.heliyon.2023.e13169