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Cholesterol metabolism and lipid droplet vacuoles; a potential target for the therapy of aggressive lymphoma

Cholesterol uptake via LDL receptor (LDLR) is increased in some malignant tumors, and incorporated LDL contribute to lipid droplet formation. Burkitt’s lymphoma is known to have a large number of vacuoles in the cytoplasm, however, intracellular vacuoles are also seen in high-grade lymphomas such as...

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Detalles Bibliográficos
Autores principales: Yano, Hiromu, Fujiwara, Yukio, Komohara, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JSLRT 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898721/
https://www.ncbi.nlm.nih.gov/pubmed/36436934
http://dx.doi.org/10.3960/jslrt.22023