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A modified mouse model of haemorrhagic transformation associated with tPA administration after thromboembolic stroke
OBJECTIVE: To establish a new mouse model of haemorrhagic transformation associated with delayed tissue-type plasminogen activator (tPA) treatment to provide a novel tool to study therapeutic strategies for haemorrhagic transformation. METHODS: Male C57BL/6 mice were subjected to carotid artery thro...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898747/ https://www.ncbi.nlm.nih.gov/pubmed/36747951 http://dx.doi.org/10.1016/j.heliyon.2023.e13102 |