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A modified mouse model of haemorrhagic transformation associated with tPA administration after thromboembolic stroke

OBJECTIVE: To establish a new mouse model of haemorrhagic transformation associated with delayed tissue-type plasminogen activator (tPA) treatment to provide a novel tool to study therapeutic strategies for haemorrhagic transformation. METHODS: Male C57BL/6 mice were subjected to carotid artery thro...

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Detalles Bibliográficos
Autores principales:	Ye, Yang, Xin, Xi-Yan, Zhang, Hao-Lin, Fan, Rui-Wen, Zhu, Yu-Tian, Li, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898747/ https://www.ncbi.nlm.nih.gov/pubmed/36747951 http://dx.doi.org/10.1016/j.heliyon.2023.e13102

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