Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity

Phosphatidylinositol (PtdIns) transfer proteins (PITPs) enhance the activities of PtdIns 4-OH kinases that generate signaling pools of PtdIns-4-phosphate. In that capacity, PITPs serve as key regulators of lipid signaling in eukaryotic cells. Although the PITP phospholipid exchange cycle is the engi...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Ru, Poudel, Lokendra, Hong, Zebin, Johnen, Philipp, Katti, Sachin, Tripathi, Ashutosh, Nile, Aaron H., Green, Savana M., Khan, Danish, Schaaf, Gabriel, Bono, Fulvia, Bankaitis, Vytas A., Igumenova, Tatyana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898755/
https://www.ncbi.nlm.nih.gov/pubmed/36603766
http://dx.doi.org/10.1016/j.jbc.2022.102861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898755/
https://www.ncbi.nlm.nih.gov/pubmed/36603766
http://dx.doi.org/10.1016/j.jbc.2022.102861

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