Analysis of a degron-containing reporter protein GFP-CL1 reveals a role for SUMO1 in cytosolic protein quality control

Misfolded proteins are recognized and degraded through protein quality control (PQC) pathways, which are essential for maintaining proteostasis and normal cellular functions. Defects in PQC can result in disease, including cancer, cardiovascular disease, and neurodegeneration. The small ubiquitin-re...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Lu, Jian, Yang, Wei-Chih, Spear, Eric D., Michaelis, Susan, Matunis, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898758/
https://www.ncbi.nlm.nih.gov/pubmed/36587767
http://dx.doi.org/10.1016/j.jbc.2022.102851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898758/
https://www.ncbi.nlm.nih.gov/pubmed/36587767
http://dx.doi.org/10.1016/j.jbc.2022.102851

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