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The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly

The Saccharomyces cerevisiae Yta7 is a chromatin remodeler harboring a histone-interacting bromodomain (BRD) and two AAA+ modules. It is not well understood how Yta7 recognizes the histone H3 tail to promote nucleosome disassembly for DNA replication or RNA transcription. By cryo-EM analysis, here w...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Feng, Xiang, He, Qing, Li, Hua, Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898759/
https://www.ncbi.nlm.nih.gov/pubmed/36592926
http://dx.doi.org/10.1016/j.jbc.2022.102852