In Outpatients Receiving Parenteral Vancomycin, Dosing Adjustments Produced by Area Under the Curve-Based and Trough-Based Monitoring Differ Only at the Extremes of the Therapeutic Trough Range

Area under the curve (AUC)-based vancomycin dosing reduces nephrotoxicity but is burdensome. Reviewing 115 adults receiving ≥2 weeks of outpatient vancomycin, we found AUC-based and trough-based dose adjustments discordant only for troughs <12 or >16 mg/L. Selective versus universal outpatient...

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Detalles Bibliográficos
Autores principales: Shi, Yufei, Alexander, Bryan T, Avedissian, Sean, Bergman, Scott J, Cortés-Penfield, Nicolás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898881/
https://www.ncbi.nlm.nih.gov/pubmed/36751644
http://dx.doi.org/10.1093/ofid/ofac696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898881/
https://www.ncbi.nlm.nih.gov/pubmed/36751644
http://dx.doi.org/10.1093/ofid/ofac696

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