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Generation of multilineage liver organoids with luminal vasculature and bile ducts from human pluripotent stem cells via modulation of Notch signaling

BACKGROUND: The generation of liver organoids recapitulating parenchymal and non-parenchymal cell interplay is essential for the precise in vitro modeling of liver diseases. Although different types of multilineage liver organoids (mLOs) have been generated from human pluripotent stem cells (hPSCs),...

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Detalles Bibliográficos
Autores principales: Kim, Hyo Jin, Kim, Gyeongmin, Chi, Kyun Yoo, Kim, Hyemin, Jang, Yu Jin, Jo, Seongyea, Lee, Jihun, Lee, Youngseok, Woo, Dong-Hun, Han, Choongseong, Kim, Sang Kyum, Park, Han-Jin, Kim, Jong-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898924/
https://www.ncbi.nlm.nih.gov/pubmed/36737811
http://dx.doi.org/10.1186/s13287-023-03235-5