Expression of integrin β-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics

BACKGROUND: Oncogenic overexpression of integrin-β7 (ITGB7) in cases of high-risk multiple myeloma (MM) was reported to promote enhanced interactions between neoplastic plasma-B cells and stromal cells to develop cell-adhesion mediated drug resistance. METHODS: Expression profiles of adhesion relate...

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Detalles Bibliográficos
Autores principales: Roy Choudhury, Samrat, Byrum, Stephanie D., Alkam, Duah, Ashby, Cody, Zhan, Fenghuang, Tackett, Alan J., Van Rhee, Frits
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898982/
https://www.ncbi.nlm.nih.gov/pubmed/36737807
http://dx.doi.org/10.1186/s13148-023-01433-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898982/
https://www.ncbi.nlm.nih.gov/pubmed/36737807
http://dx.doi.org/10.1186/s13148-023-01433-9

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