Cargando…

Expression of integrin β-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics

BACKGROUND: Oncogenic overexpression of integrin-β7 (ITGB7) in cases of high-risk multiple myeloma (MM) was reported to promote enhanced interactions between neoplastic plasma-B cells and stromal cells to develop cell-adhesion mediated drug resistance. METHODS: Expression profiles of adhesion relate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roy Choudhury, Samrat, Byrum, Stephanie D., Alkam, Duah, Ashby, Cody, Zhan, Fenghuang, Tackett, Alan J., Van Rhee, Frits
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898982/ https://www.ncbi.nlm.nih.gov/pubmed/36737807 http://dx.doi.org/10.1186/s13148-023-01433-9

Ejemplares similares

Epigenetic Deregulation of Telomere-Related Genes in Newly Diagnosed Multiple Myeloma Patients
por: Roy Choudhury, Samrat, et al.
Publicado: (2021)

The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma
por: Choudhury, Samrat Roy, et al.
Publicado: (2020)

Genetic Analysis of Multiple Myeloma Identifies Cytogenetic Alterations Implicated in Disease Complexity and Progression
por: Li, Can, et al.
Publicado: (2021)

Daratumumab, lenalidomide, and dexamethasone in relapsed/refractory myeloma: a cytogenetic subgroup analysis of POLLUX
por: Kaufman, Jonathan L., et al.
Publicado: (2020)

3195 Genomic Analysis of Primary Plasma Cell Leukemia reveals Complex Cytogenetic Alterations and High Risk Mutational Patterns
por: Schinke, Carolina, et al.
Publicado: (2019)

Daratumumab, bortezomib, and dexamethasone in relapsed or refractory multiple myeloma: subgroup analysis of CASTOR based on cytogenetic risk
por: Weisel, Katja, et al.
Publicado: (2020)

Subgroup analysis of ICARIA‐MM study in relapsed/refractory multiple myeloma patients with high‐risk cytogenetics
por: Harrison, Simon J., et al.
Publicado: (2021)

The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma
por: Boyle, Eileen M., et al.
Publicado: (2021)

Risk of infections associated with the use of bispecific antibodies in multiple myeloma: a pooled analysis
por: Mazahreh, Farah, et al.
Publicado: (2023)

Geographic and Racial Disparities in Access to Chimeric Antigen Receptor–T Cells and Bispecific Antibodies Trials for Multiple Myeloma
por: Alqazaqi, Raghad, et al.
Publicado: (2022)

Isatuximab plus carfilzomib and dexamethasone in relapsed multiple myeloma patients with high‐risk cytogenetics: IKEMA subgroup analysis
por: Spicka, Ivan, et al.
Publicado: (2022)

CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation
por: Gai, Dongzheng, et al.
Publicado: (2022)

A gene signature can predict risk of MGUS progressing to multiple myeloma
por: Sun, Fumou, et al.
Publicado: (2023)

Variability of definition of high‐risk multiple myeloma across phase III clinical trials
por: Abu Za'nouneh, Faris Jamal, et al.
Publicado: (2023)

Smoking and the risk of acute myeloid leukaemia in cytogenetic subgroups
por: Moorman, A V, et al.
Publicado: (2002)

P931: ISATUXIMAB IN RELAPSED MULTIPLE MYELOMA PATIENTS WITH ULTRA-HIGH-RISK CYTOGENETICS: ICARIA-MM AND IKEMA SUBGROUP ANALYSIS
por: Moreau, Philippe, et al.
Publicado: (2023)

Quantitative analysis of histone exchange for transcriptionally active chromatin
por: Byrum, Stephanie D, et al.
Publicado: (2011)

Purification of a specific native genomic locus for proteomic analysis
por: Byrum, Stephanie D., et al.
Publicado: (2013)

CRISPR/dCas9-KRAB-Mediated Suppression of S100b Restores p53-Mediated Apoptosis in Melanoma Cells
por: Roy Choudhury, Samrat, et al.
Publicado: (2023)

Genetics, Cytogenetics, and Epigenetics of Colorectal Cancer
por: Migliore, Lucia, et al.
Publicado: (2011)

PB2081: CYTOGENETICS OF MULTIPLE MYELOMA IN MOROCCO
por: Moutmir, Yasmine, et al.
Publicado: (2023)

Integrins in multiple myeloma
por: Hosen, Naoki
Publicado: (2020)

Cold Storage Increases Albumin and Advanced Glycation-End Product-Albumin Levels in Kidney Transplants: A Possible Cause for Exacerbated Renal Damage
por: Lo, Sorena, et al.
Publicado: (2019)

Interpretation of cytogenetic results in multiple myeloma for clinical practice
por: Rajan, A M, et al.
Publicado: (2015)

Epigenetic Editing of Ascl1 Gene in Neural Stem Cells by Optogenetics
por: Lo, Chiao-Ling, et al.
Publicado: (2017)

Chimeric antigen receptor T cell therapies for multiple myeloma
por: Wu, Chao, et al.
Publicado: (2019)

High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
por: Cheng, Yan, et al.
Publicado: (2023)

Expression levels of HMGA2 in adipocytic tumors correlate with morphologic and cytogenetic subgroups
por: Bartuma, Hammurabi, et al.
Publicado: (2009)

Increased Oxidative Damage Associated with Unfavorable Cytogenetic Subgroups in Chronic Lymphocytic Leukemia
por: Collado, Rosa, et al.
Publicado: (2014)

Selective increase in subtelomeric DNA methylation: an epigenetic biomarker for malignant glioma
por: Choudhury, Samrat Roy, et al.
Publicado: (2015)

Differential Analysis of Genetic, Epigenetic, and Cytogenetic Abnormalities in AML
por: Islam, Mirazul, et al.
Publicado: (2017)

Immunogenicity of Covid-19 Vaccine Among Multiple Myeloma Patients Post Autologous Stem Cell Transplant
por: Thalambedu, Nishanth, et al.
Publicado: (2023)

Conventional and Molecular Cytogenetic Analyses in Turkish Patients with Multiple Myeloma
por: Durak, Beyhan Aras, et al.
Publicado: (2012)

Occurrence and prognostic significance of cytogenetic evolution in patients with multiple myeloma
por: Binder, M, et al.
Publicado: (2016)

Clinicopathological Characteristics of Hyperdiploidy with High-Risk Cytogenetics in Multiple Myeloma
por: Yang, Naery, et al.
Publicado: (2018)

Cytogenetic and FISH analysis of 93 multiple myeloma Moroccan patients
por: Hamdaoui, Hasna, et al.
Publicado: (2020)

Multiple myeloma with high-risk cytogenetics and its treatment approach
por: Hanamura, Ichiro
Publicado: (2022)

Mouse models of human multiple myeloma subgroups
por: Winkler, Wiebke, et al.
Publicado: (2023)

Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?
por: Franqui-Machin, Reinaldo, et al.
Publicado: (2015)

Immunogenicity of Covid-19 Vaccine Among Multiple Myeloma Patients Post Autologous Stem Cell Transplant
por: Thalambedu, Nishanth, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_trmppp33jplbn7hgo46nfpmtdl