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The immunoregulatory protein CD200 as a potentially lucrative yet elusive target for cancer therapy

CD200 is an immunoregulatory cell surface ligand with proven pro-tumorigenic credentials via its ability to suppress CD200 receptor (CD200R)-expressing anti-tumor immune function. This definitive role for the CD200-CD200R axis in regulating an immunosuppressive tumor microenvironment has garnered in...

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Detalles Bibliográficos
Autores principales: Shao, Anqi, Owens, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899099/
https://www.ncbi.nlm.nih.gov/pubmed/36738455
http://dx.doi.org/10.18632/oncotarget.28354