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Coordinated local RNA overexpression of complement induced by interferon gamma in myositis

Complement proteins are deposited in the muscles of patients with myositis. However, the local expression and regulation of complement genes within myositis muscle have not been well characterized. In this study, bulk RNA sequencing (RNAseq) analyses of muscle biopsy specimens revealed that compleme...

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Detalles Bibliográficos
Autores principales: Casal-Dominguez, Maria, Pinal-Fernandez, Iago, Pak, Katherine, Muñoz-Braceras, Sandra, Milisenda, Jose C., Torres-Ruiz, Jiram, Dell′Orso, Stefania, Naz, Faiza, Gutierrez-Cruz, Gustavo, Duque-Jaimez, Yaiza, Matas-Garcia, Ana, Valls-Roca, Laura, Garrabou, Gloria, Trallero-Araguas, Ernesto, Walitt, Brian, Christopher-Stine, Lisa, Lloyd, Thomas E., Paik, Julie J., Albayda, Jemima, Corse, Andrea, Grau, Josep Maria, Selva-O’Callaghan, Albert, Mammen, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899209/
https://www.ncbi.nlm.nih.gov/pubmed/36739295
http://dx.doi.org/10.1038/s41598-023-28838-z