Cell surface-bound La protein regulates the cell fusion stage of osteoclastogenesis

Multinucleated osteoclasts, essential for skeletal remodeling in health and disease, are formed by the fusion of osteoclast precursors, where each fusion event raises their bone-resorbing activity. Here we show that the nuclear RNA chaperone, La protein has an additional function as an osteoclast fu...

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Detalles Bibliográficos
Autores principales: Whitlock, Jarred M., Leikina, Evgenia, Melikov, Kamran, De Castro, Luis Fernandez, Mattijssen, Sandy, Maraia, Richard J., Collins, Michael T., Chernomordik, Leonid V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899215/
https://www.ncbi.nlm.nih.gov/pubmed/36739273
http://dx.doi.org/10.1038/s41467-023-36168-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899215/
https://www.ncbi.nlm.nih.gov/pubmed/36739273
http://dx.doi.org/10.1038/s41467-023-36168-x

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