Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1–42 in Alzheimer’s disease

Reduced insulin-like growth factor 2 (IGF2) levels in Alzheimer’s disease (AD) may be the mechanism relating age-related metabolic disorders to dementia. Since Igf2 is an imprinted gene, we examined age and sex differences in the relationship between amyloid-beta 1–42 (Aβ(42)) accumulation and epige...

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Detalles Bibliográficos
Autores principales: Fertan, Emre, Gendron, William H., Wong, Aimée A., Hanson, Gabrielle M., Brown, Richard E., Weaver, Ian C. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899226/
https://www.ncbi.nlm.nih.gov/pubmed/36739453
http://dx.doi.org/10.1038/s41598-023-29248-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899226/
https://www.ncbi.nlm.nih.gov/pubmed/36739453
http://dx.doi.org/10.1038/s41598-023-29248-x

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