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Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1–42 in Alzheimer’s disease
Reduced insulin-like growth factor 2 (IGF2) levels in Alzheimer’s disease (AD) may be the mechanism relating age-related metabolic disorders to dementia. Since Igf2 is an imprinted gene, we examined age and sex differences in the relationship between amyloid-beta 1–42 (Aβ(42)) accumulation and epige...
Autores principales: | Fertan, Emre, Gendron, William H., Wong, Aimée A., Hanson, Gabrielle M., Brown, Richard E., Weaver, Ian C. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899226/ https://www.ncbi.nlm.nih.gov/pubmed/36739453 http://dx.doi.org/10.1038/s41598-023-29248-x |
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