Blocking of PI3-kinase beta protects against cerebral ischemia/reperfusion injury by reducing platelet activation and downstream microvascular thrombosis in rats

Phosphoinositide 3-kinase beta (PI3Kβ) plays an important role in platelet activation and thrombosis, but its role in stroke pathology remains unknown. In this study, we investigated whether inhibition of PI3Kβ protects against cerebral ischemia/reperfusion (I/R) injury by preventing circulating pla...

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Detalles Bibliográficos
Autores principales: Cheng, Qiong, Wang, Min, Jin, Rong, Li, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899241/
https://www.ncbi.nlm.nih.gov/pubmed/36739310
http://dx.doi.org/10.1038/s41598-023-29235-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899241/
https://www.ncbi.nlm.nih.gov/pubmed/36739310
http://dx.doi.org/10.1038/s41598-023-29235-2

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