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An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice

Genetically encoded Ca(2+) indicators (GECIs) are widely used to measure neural activity. Here, we explore the use of systemically administered PHP.eB AAVs for brain-wide expression of GECIs and compare the expression properties to intracerebrally injected AAVs in male mice. We show that systemic ad...

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Detalles Bibliográficos
Autores principales: Grødem, Sverre, Nymoen, Ingeborg, Vatne, Guro Helén, Rogge, Frederik Sebastian, Björnsdóttir, Valgerður, Lensjø, Kristian Kinden, Fyhn, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899252/
https://www.ncbi.nlm.nih.gov/pubmed/36739289
http://dx.doi.org/10.1038/s41467-023-36324-3