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VHL-HIF-2α axis-induced SEMA6A upregulation stabilized β-catenin to drive clear cell renal cell carcinoma progression

SEMA6A is a multifunctional transmembrane semaphorin protein that participates in various cellular processes, including axon guidance, cell migration, and cancer progression. However, the role of SEMA6A in clear cell renal cell carcinoma (ccRCC) is unclear. Based on high-throughput sequencing data,...

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Detalles Bibliográficos
Autores principales: Ji, Jing, Xu, Yuxin, Xie, Mengru, He, Xingbei, Ren, Dexu, Qiu, Teng, Liu, Wenwen, Chen, Zefeng, Shi, Wen, Zhang, Zhen, Wang, Xiujun, Wang, Weiling, Ma, Jinming, Qian, Qilan, Jing, Aixin, Ma, Xinhui, Qin, Jingting, Ding, Yuanyuan, Geng, Ting, Yang, Jiayan, Sun, Zhichao, Liu, Wei, Liu, Shunfang, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899268/
https://www.ncbi.nlm.nih.gov/pubmed/36739418
http://dx.doi.org/10.1038/s41419-023-05588-4