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Macromolecular crowding regulates matrix composition and gene expression in human gingival fibroblast cultures

Standard cell cultures are performed in aqueous media with a low macromolecule concentration compared to tissue microenvironment. In macromolecular crowding (MMC) experiments, synthetic polymeric crowders are added into cell culture media to better mimic macromolecule concentrations found in vivo. H...

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Detalles Bibliográficos
Autores principales: Ramalingam, Rajesvaran, Jiang, Guoqiao, Larjava, Hannu, Häkkinen, Lari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899282/
https://www.ncbi.nlm.nih.gov/pubmed/36739306
http://dx.doi.org/10.1038/s41598-023-29252-1