Endothelial Toll-like receptor 4 is required for microglia activation in the murine retina after systemic lipopolysaccharide exposure

BACKGROUND: Clustering of microglia around the vasculature has been reported in the retina and the brain after systemic administration of lipopolysaccharides (LPS) in mice. LPS acts via activation of Toll-like receptor 4 (TRL4), which is expressed in several cell types including microglia, monocytes...

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Detalles Bibliográficos
Autores principales: Tsioti, Ioanna, Steiner, Beatrice L., Escher, Pascal, Zinkernagel, Martin S., Benz, Peter M., Kokona, Despina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899393/
https://www.ncbi.nlm.nih.gov/pubmed/36739425
http://dx.doi.org/10.1186/s12974-023-02712-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899393/
https://www.ncbi.nlm.nih.gov/pubmed/36739425
http://dx.doi.org/10.1186/s12974-023-02712-1

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