Sirt3 restricts tumor initiation via promoting LONP1 deacetylation and K63 ubiquitination

BACKGROUND: Sirtuin 3 (Sirt3) is a controversial regulator of carcinogenesis. It residents in the mitochondria and gradually decays during aging. In this study, we tried to investigate the role of Sirt3 in carcinogenesis and to explore its involvement in metabolic alteration. METHODS: We generated c...

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Detalles Bibliográficos
Autores principales: Wu, Liyi, Yan, Xinyi, Sun, Ruibo, Ma, Ye, Yao, Wanyu, Gao, Baogui, Zhang, Qingyuan, You, Junxiong, Wang, Hao, Han, Qinrui, Sun, Xuegang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899405/
https://www.ncbi.nlm.nih.gov/pubmed/36739437
http://dx.doi.org/10.1186/s12967-023-03925-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899405/
https://www.ncbi.nlm.nih.gov/pubmed/36739437
http://dx.doi.org/10.1186/s12967-023-03925-x

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