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Mitogen‐activated protein kinase inhibition augments the T cell response against HOXB7‐expressing tumor through human leukocyte antigen upregulation

Homeobox B7 (HOXB7) is a master regulatory gene that regulates cell proliferation and activates oncogenic pathways. Overexpression of HOXB7 correlates with aggressive behavior and poor prognosis in patients with cancer. However, the expression and role of HOXB7 in head and neck squamous cell carcino...

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Detalles Bibliográficos
Autores principales: Komatsuda, Hiroki, Wakisaka, Risa, Kono, Michihisa, Kumai, Takumi, Hayashi, Ryusuke, Yamaki, Hidekiyo, Sato, Ryosuke, Nagato, Toshihiro, Ohkuri, Takayuki, Kosaka, Akemi, Ohara, Kenzo, Takahara, Miki, Katada, Akihiro, Kobayashi, Hiroya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899601/
https://www.ncbi.nlm.nih.gov/pubmed/36285482
http://dx.doi.org/10.1111/cas.15619