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TAS2940, a novel brain‐penetrable pan‐ERBB inhibitor, for tumors with HER2 and EGFR aberrations

Genetic alterations in human epidermal growth factor receptor type 2 (HER2)/epidermal growth factor receptor (EGFR) are commonly associated with breast and lung cancers and glioblastomas. Cancers with avian erythroblastosis oncogene B (ERBB) deregulation are highly metastatic and can cause primary b...

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Detalles Bibliográficos
Autores principales: Oguchi, Kei, Araki, Hikari, Tsuji, Shingo, Nakamura, Masayuki, Miura, Akihiro, Funabashi, Kaoru, Osada, Akiko, Tanaka, Sakiho, Suzuki, Takamasa, Kobayashi, Susumu S., Mizuarai, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899605/
https://www.ncbi.nlm.nih.gov/pubmed/36282234
http://dx.doi.org/10.1111/cas.15617