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S‐1 eliminates MDSCs and enhances the efficacy of PD‐1 blockade via regulation of tumor‐derived Bv8 and S100A8 in thoracic tumor

Myeloid‐derived suppressor cells (MDSCs) have been known to play a pivotal role in the induction of immune tolerance, which limits the benefits of immune checkpoint inhibitors (ICIs). Recent studies revealed that several chemotherapeutic agents decreased tumor‐infiltrating MDSCs. Therefore, combinat...

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Detalles Bibliográficos
Autores principales: Nguyen, Na T., Mitsuhashi, Atsushi, Ogino, Hirokazu, Kozai, Hiroyuki, Yoneda, Hiroto, Afroj, Tania, Sato, Seidai, Nokihara, Hiroshi, Shinohara, Tsutomu, Nishioka, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899614/
https://www.ncbi.nlm.nih.gov/pubmed/36285504
http://dx.doi.org/10.1111/cas.15620