Cargando…

Proteolytic cleavage of membrane proteins by membrane type‐1 MMP regulates cancer malignant progression

Strategies to develop cancer therapies using inhibitors that target matrix metalloproteinases (MMPs), particularly membrane type‐1 MMP (MT1‐MMP), have failed. This is predominantly attributed to the specificity of MMP inhibitors and numerous functions of MMPs; therefore, targeting substrates with su...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ikeda, Kazuki, Kaneko, Ryo, Tsukamoto, Eiki, Funahashi, Nobuaki, Koshikawa, Naohiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899627/ https://www.ncbi.nlm.nih.gov/pubmed/36336966 http://dx.doi.org/10.1111/cas.15638

Ejemplares similares

Bilayer Membrane Modulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Structure and Proteolytic Activity
por: Cerofolini, Linda, et al.
Publicado: (2016)

Membrane-Type 4 Matrix Metalloproteinase (MT4-MMP) Modulates Water Homeostasis in Mice
por: Srichai, Manakan B., et al.
Publicado: (2011)

Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases
por: Chen, Li-Mei, et al.
Publicado: (2017)

A novel regulation of PD-1 ligands on mesenchymal stromal cells through MMP-mediated proteolytic cleavage
por: Dezutter-Dambuyant, Colette, et al.
Publicado: (2015)

Proteolytic cleavage of haptoglobin occurs in a subcompartment of the endoplasmic reticulum: evidence from membrane fusion in vitro
Publicado: (1993)

Proteolytic Cleavage of Receptor Tyrosine Kinases
por: Huang, Hao
Publicado: (2021)

MT1-MMP-dependent cell migration: proteolytic and non-proteolytic mechanisms
por: Gifford, Valentina, et al.
Publicado: (2019)

Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration
por: Bieri, Gregor, et al.
Publicado: (2018)

Proteolytic α-Synuclein Cleavage in Health and Disease
por: Bluhm, Alexandra, et al.
Publicado: (2021)

MMP proteolytic activity regulates cancer invasiveness by modulating integrins
por: Das, Alakesh, et al.
Publicado: (2017)

Installation of authentic BicA and SbtA proteins to the chloroplast envelope membrane is achieved by the proteolytic cleavage of chimeric proteins in Arabidopsis
por: Uehara, Susumu, et al.
Publicado: (2020)

Activation of MMP‐9 by membrane type‐1 MMP/MMP‐2 axis stimulates tumor metastasis
por: Li, Zichen, et al.
Publicado: (2017)

Proteolytic Cleavage of Apolipoprotein E in the Down Syndrome Brain
por: Day, Ryan J., et al.
Publicado: (2016)

Fungal gasdermin-like proteins are controlled by proteolytic cleavage
por: Clavé, Corinne, et al.
Publicado: (2022)

EphA2 Proteolytic Fragment as a Sensitive Diagnostic Biomarker for Very Early-stage Pancreatic Ductal Carcinoma
por: Sato, Shinya, et al.
Publicado: (2023)

Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage
por: Griparic, Lorena, et al.
Publicado: (2007)

Microcin PDI regulation and proteolytic cleavage are unique among known microcins
por: Zhao, Zhe, et al.
Publicado: (2017)

Proteolytic chemokine cleavage as a regulator of lymphocytic infiltration in solid tumors
por: Bronger, Holger, et al.
Publicado: (2019)

Proteolytic Activation of Plant Membrane-Bound Transcription Factors
por: De Backer, Jonas, et al.
Publicado: (2022)

Critical Role of Transient Activity of MT1-MMP for ECM Degradation in Invadopodia
por: Watanabe, Ayako, et al.
Publicado: (2013)

Role of Cell Surface Metalloprotease Mt1-Mmp in Epithelial Cell Migration over Laminin-5
por: Koshikawa, Naohiko, et al.
Publicado: (2000)

Correction: Critical Role of Transient Activity of MT1-MMP for ECM Degradation in Invadopodia
por: Watanabe, Ayako, et al.
Publicado: (2013)

Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas
por: Forsyth, P A, et al.
Publicado: (1999)

Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation
por: Kwak, Hyeong-Il, et al.
Publicado: (2012)

Proteolytic cleavage of p53 mutants in response to mismatched DNA
por: Mee, T, et al.
Publicado: (1999)

Correct proteolytic cleavage is required for the cell adhesive function of uvomorulin
Publicado: (1990)

Requirements for Efficient Proteolytic Cleavage of Prelamin A by ZMPSTE24
por: Barrowman, Jemima, et al.
Publicado: (2012)

Cleavage of HMGB1 by Proteolytic Enzymes Associated with Inflammatory Conditions
por: Sowinska, Agnieszka, et al.
Publicado: (2020)

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
por: Jin, Seok Min, et al.
Publicado: (2010)

Mapping Proteolytic Processing in the Secretome of Gastric Cancer-Associated Myofibroblasts Reveals Activation of MMP-1, MMP-2, and MMP-3
por: Holmberg, Christopher, et al.
Publicado: (2013)

Membrane-type 1 Matrix Metalloproteinase Modulates Tissue Homeostasis by a Non-proteolytic Mechanism
por: Attur, Mukundan, et al.
Publicado: (2020)

STUDIES ON FERMENT ACTION : V. IMMUNIZATION WITH PROTEOLYTIC CLEAVAGE PRODUCTS OF PNEUMOCOCCI.
por: Jobling, James W., et al.
Publicado: (1912)

A pathway sensor for genome-wide screens of intracellular proteolytic cleavage
por: Ketteler, Robin, et al.
Publicado: (2008)

Proteolytic cleavage is required for functional neuroligin 2 maturation and trafficking in Drosophila
por: Tu, Renjun, et al.
Publicado: (2017)

Neutrophils and Activated Macrophages Control Mucosal Immunity by Proteolytic Cleavage of Antileukoproteinase
por: Vandooren, Jennifer, et al.
Publicado: (2018)

Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage
por: Kumar, Senthil T., et al.
Publicado: (2023)

Expression of Cancer Stem Cell Markers EpCAM and CD90 Is Correlated with Anti- and Pro-Oncogenic EphA2 Signaling in Hepatocellular Carcinoma
por: Asakura, Nobuhiko, et al.
Publicado: (2021)

Establishment and Validation of Computational Model for MT1-MMP Dependent ECM Degradation and Intervention Strategies
por: Hoshino, Daisuke, et al.
Publicado: (2012)

Developmental expression of membrane type 4-matrix metalloproteinase (Mt4-mmp/Mmp17) in the mouse embryo
por: Blanco, María José, et al.
Publicado: (2017)

Dynamic Expression of Membrane Type 1-Matrix Metalloproteinase (Mt1-mmp/Mmp14) in the Mouse Embryo
por: Muñoz-Sáez, Emma, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vl02ar12n2trbl8g7v6bk3cppb