YAP/TAZ activation predicts clinical outcomes in mesothelioma and is conserved in in vitro model of driver mutations

The Hippo signalling pathway is dysregulated across a wide range of cancer types and, although driver mutations that directly affect the core Hippo components are rare, a handful is found within pleural mesothelioma (PM). PM is a deadly disease of the lining of the lung caused by asbestos exposure....

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Detalles Bibliográficos
Autores principales: Cunningham, Richard, Jia, Siyang, Purohit, Krishna, Salem, Omar, Hui, Ning Sze, Lin, Yue, Carragher, Neil O., Hansen, Carsten Gram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899629/
https://www.ncbi.nlm.nih.gov/pubmed/36740402
http://dx.doi.org/10.1002/ctm2.1190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899629/
https://www.ncbi.nlm.nih.gov/pubmed/36740402
http://dx.doi.org/10.1002/ctm2.1190

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