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Evaluating the transduction efficiency of systemically delivered AAV vectors in the rat nervous system

Gene delivery or manipulation with viral vectors is a frequently used tool in basic neuroscience studies. Adeno-associated viruses (AAV) are the most widely used vectors due to their relative safety and long-term efficacy without causing overt immunological complications. Many AAV serotypes have bee...

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Detalles Bibliográficos
Autores principales: Yang, Olivia J., Robilotto, Gabriella L., Alom, Firoj, Alemán, Karla, Devulapally, Karthik, Morris, Abigail, Mickle, Aaron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899837/
https://www.ncbi.nlm.nih.gov/pubmed/36755734
http://dx.doi.org/10.3389/fnins.2023.1001007