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Intracellular virion traffic to the endosome driven by cell type specific sialic acid receptors determines parvovirus tropism

Parvoviruses are promising anticancer and gene therapy agents, but a deep knowledge of the entry process is crucial to exploit their therapeutic potential. We addressed this issue while attempting to retarget the oncolytic parvovirus minute virus of mice (MVMp) to the tumor vasculature. Residues at...

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Detalles Bibliográficos
Autores principales: Calvo-López, Tania, Grueso, Esther, Sánchez-Martínez, Cristina, Almendral, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899843/
https://www.ncbi.nlm.nih.gov/pubmed/36756201
http://dx.doi.org/10.3389/fmicb.2022.1063706