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Estrogen receptor β/substance P signaling in spinal cord mediates antinociceptive effect in a mouse model of discogenic low back pain

INTRODUCTION: Discogenic low back pain (DLBP) is the most commonly described form of back pain. Our previous studies indicated that estrogen-dependent DLBP mechanism was mediated by estrogen receptors (ERs) in the intervertebral disc (IVD) tissue, and the IVD degeneration degree is accompanied by do...

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Detalles Bibliográficos
Autores principales: Song, Xiao-Xing, Jin, Lin-Yu, Li, Qiang, Li, Xin-Feng, Luo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899865/
https://www.ncbi.nlm.nih.gov/pubmed/36756381
http://dx.doi.org/10.3389/fncel.2022.1071012