Cargando…

Development of sandwich ELISAs for detecting glucagon-like peptide-1 secretion from intestinal L-cells and their application in STC-1 cells and mice

Certain nutrients stimulate glucagon-like peptide-1 (GLP-1) secretion from the intestinal enteroendocrine L-cells, but due to rapid degradation by the DPP-4 enzyme, >90% is converted to inactive metabolite before reaching the target organs via circulation. Plants are a source of potent bioactive...

Descripción completa

Detalles Bibliográficos
Autores principales: Odongo, Kevin, Hironao, Ken-yu, Yamashita, Yoko, Ashida, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899920/
https://www.ncbi.nlm.nih.gov/pubmed/36777078
http://dx.doi.org/10.3164/jcbn.22-78