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Expression of FMD virus-like particles in yeast Hansenula polymorpha and immunogenicity of combine with CpG and aluminum adjuvant

BACKGROUND: Inactivated vaccines are limited in preventing foot-and-mouth disease (FMD) due to safety problems. Recombinant virus-like particles (VLPs) are an excellent candidate for a novel vaccine for preventing FMD, given that VLPs have similar immunogenicity as natural viruses and are replicatio...

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Detalles Bibliográficos
Autores principales: Zhang, Jianhui, Ge, Jun, Li, Juyin, Li, Jianqiang, Zhang, Yong, Shi, Yinghui, Sun, Jiaojiao, Wang, Qiongjin, Zhang, Xiaobo, Zhao, Xingxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899949/
https://www.ncbi.nlm.nih.gov/pubmed/36726280
http://dx.doi.org/10.4142/jvs.22227