Leptin accelerates BMSC transformation into vertebral epiphyseal plate chondrocytes by activating SENP1‐mediated deSUMOylation of SIRT3

Bone marrow mesenchymal stem cells (BMSCs) are capable of multidirectional differentiation, and engrafted BMSCs can be used to replace damaged chondrocytes for treatment of intervertebral disc disease. However, chondroblast differentiation of implanted BMSCs is inhibited by the anoxic environment of...

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Detalles Bibliográficos
Autores principales: Li, Xiaomiao, Fu, Xiaodong, Li, Hao, Gao, Yingjian, Wang, Weili, Liu, Zude, Shen, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900084/
https://www.ncbi.nlm.nih.gov/pubmed/36537765
http://dx.doi.org/10.1002/2211-5463.13539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900084/
https://www.ncbi.nlm.nih.gov/pubmed/36537765
http://dx.doi.org/10.1002/2211-5463.13539

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