Cargando…

Leptin accelerates BMSC transformation into vertebral epiphyseal plate chondrocytes by activating SENP1‐mediated deSUMOylation of SIRT3

Bone marrow mesenchymal stem cells (BMSCs) are capable of multidirectional differentiation, and engrafted BMSCs can be used to replace damaged chondrocytes for treatment of intervertebral disc disease. However, chondroblast differentiation of implanted BMSCs is inhibited by the anoxic environment of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xiaomiao, Fu, Xiaodong, Li, Hao, Gao, Yingjian, Wang, Weili, Liu, Zude, Shen, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900084/ https://www.ncbi.nlm.nih.gov/pubmed/36537765 http://dx.doi.org/10.1002/2211-5463.13539

Ejemplares similares

SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis
por: Yu, Luyang, et al.
Publicado: (2010)

Protective role of the deSUMOylating enzyme SENP3 in myocardial ischemia-reperfusion injury
por: Rawlings, Nadiia, et al.
Publicado: (2019)

SENP1 Is a Crucial Regulator for Cell Senescence through DeSUMOylation of Bmi1
por: Xia, Nansong, et al.
Publicado: (2016)

SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
por: Yu, Xiaoyan, et al.
Publicado: (2018)

SENP1 is a crucial promotor for hepatocellular carcinoma through deSUMOylation of UBE2T
por: Tao, Yifeng, et al.
Publicado: (2020)

SENP3-mediated deSUMOylation of Drp1 facilitates interaction with Mff to promote cell death
por: Guo, Chun, et al.
Publicado: (2017)

SENP6-Mediated deSUMOylation of VEGFR2 Enhances Its Cell Membrane Transport in Angiogenesis
por: He, Qi, et al.
Publicado: (2023)

SENP6 regulates localization and nuclear condensation of DNA damage response proteins by group deSUMOylation
por: Claessens, Laura A., et al.
Publicado: (2023)

SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia
por: Guo, Chun, et al.
Publicado: (2013)

SENP1-mediated NEMO deSUMOylation in adipocytes limits inflammatory responses and type-1 diabetes progression
por: Shao, Lan, et al.
Publicado: (2015)

The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis
por: Qiu, Cong, et al.
Publicado: (2017)

SENP1-mediated deSUMOylation of JAK2 regulates its kinase activity and platinum drug resistance
por: Li, Jing, et al.
Publicado: (2021)

SENP3‐mediated TIP60 deSUMOylation is required for DNA‐PKcs activity and DNA damage repair
por: Han, Yang, et al.
Publicado: (2022)

SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
por: Cui, Chun-Ping, et al.
Publicado: (2017)

Correction to: SENP3‐mediated TIP60 deSUMOylation is required for DNA‐PKcs activity and DNA damage repair
Publicado: (2022)

SENP1-mediated deSUMOylation of USP28 regulated HIF-1α accumulation and activation during hypoxia response
por: Du, Shi-chun, et al.
Publicado: (2019)

The poly-SUMO2/3 protease SENP6 enables assembly of the constitutive centromere-associated network by group deSUMOylation
por: Liebelt, Frauke, et al.
Publicado: (2019)

Hypoxia protects H9c2 cells against Ferroptosis through SENP1-mediated protein DeSUMOylation
por: Bai, Yu-Ting, et al.
Publicado: (2021)

Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development
por: Yamada, Seiya, et al.
Publicado: (2021)

SENP3 affects the expression of PYCR1 to promote bladder cancer proliferation and EMT transformation by deSUMOylation of STAT3
por: Li, Zhuo, et al.
Publicado: (2022)

SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury
por: Xia, Qian, et al.
Publicado: (2023)

Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation
por: Abdel-Hafiz, Hany A, et al.
Publicado: (2012)

DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages
por: Lao, Yimin, et al.
Publicado: (2018)

SENP2-mediated SERCA2a deSUMOylation increases calcium overload in cardiomyocytes to aggravate myocardial ischemia/reperfusion injury
por: Luo, Yuanyuan, et al.
Publicado: (2023)

SENP3-Mediated PPARγ2 DeSUMOylation in BM-MSCs Potentiates Glucocorticoid-Induced Osteoporosis by Promoting Adipogenesis and Weakening Osteogenesis
por: Zhang, Yongxing, et al.
Publicado: (2021)

SENP3 Aggravates Renal Tubular Epithelial Cell Apoptosis in Lipopolysaccharide-Induced Acute Kidney Injury via deSUMOylation of Drp1
por: Wang, Lirui, et al.
Publicado: (2022)

SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation
por: Liu, Tingting, et al.
Publicado: (2023)

SENP1 promotes triple-negative breast cancer invasion and metastasis via enhancing CSN5 transcription mediated by GATA1 deSUMOylation
por: Gao, Yongchang, et al.
Publicado: (2022)

DeSUMOylation Controls Insulin Exocytosis in Response to Metabolic Signals
por: Vergari, Elisa, et al.
Publicado: (2012)

SENP1 and SENP2 regulate SUMOylation of amyloid precursor protein
por: Maruyama, Takuma, et al.
Publicado: (2018)

Leptin differentially regulates chondrogenesis in mouse vertebral and tibial growth plates
por: Yu, Bo, et al.
Publicado: (2017)

SENP1 and SENP2 affect spatial and temporal control of sumoylation in mitosis
por: Cubeñas-Potts, Caelin, et al.
Publicado: (2013)

Research progress on the mechanism of interleukin-1β on epiphyseal plate chondrocytes
por: Tong, Ziyuan, et al.
Publicado: (2022)

Hypoxia-induced NFATc3 deSUMOylation enhances pancreatic carcinoma progression
por: Tong, Yingying, et al.
Publicado: (2022)

SENP1-Mediated Desumoylation of DBC1 Inhibits Apoptosis Induced by High Glucose in Bovine Retinal Pericytes
por: Gao, Jian, et al.
Publicado: (2016)

Kainate receptor activation induces glycine receptor endocytosis through PKC deSUMOylation
por: Sun, Hao, et al.
Publicado: (2014)

Inhibition of p53 deSUMOylation Exacerbates Puromycin Aminonucleoside-Induced Apoptosis in Podocytes
por: Wang, Lingyu, et al.
Publicado: (2014)

Revised nomenclature and functional overview of the ULP gene family of plant deSUMOylating proteases
por: Castro, Pedro Humberto, et al.
Publicado: (2018)

DeSUMOylation of Apoptosis Inhibitor 5 by Avibirnavirus VP3 Supports Virus Replication
por: Deng, Tingjuan, et al.
Publicado: (2021)

SENP1 participates in the dynamic regulation of Elk-1 SUMOylation
por: Witty, James, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_1haofk54icllueofl0nkknol0d