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Transcription factor TFII-I fine tunes innate properties of B lymphocytes

The ubiquitously expressed transcription factor TFII-I is a multifunctional protein with pleiotropic roles in gene regulation. TFII-I associated polymorphisms are implicated in Sjögren’s syndrome and Lupus in humans and, germline deletion of the Gtf2i gene in mice leads to embryonic lethality. Here...

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Detalles Bibliográficos
Autores principales: Singh, Amit, Kaileh, Mary, De, Supriyo, Mazan-Mamczarz, Krystyna, Bayarsaihan, Dashzeveg, Sen, Ranjan, Roy, Ananda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900109/
https://www.ncbi.nlm.nih.gov/pubmed/36756127
http://dx.doi.org/10.3389/fimmu.2023.1067459