AVE 0991 Suppresses Astrocyte-Mediated Neuroinflammation of Alzheimer’s Disease by Enhancing Autophagy

PURPOSE: Our previous study has shown that AVE 0991, a nonpeptide analogue of Ang-(1-7), ameliorates cognitive decline and inhibits NLRP3 inflammasome of astrocytes in Alzheimer’s disease model mice. Additionally, several studies have suggested that activation of autophagy appears to effectively inh...

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Detalles Bibliográficos
Autores principales: Deng, Yang, Wang, Si-Yu, Wang, Qing-Guang, Xu, Zhao-Han, Peng, Qiang, Chen, Shuai-Yu, Zhu, Lin, Zhang, Ying-Dong, Duan, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900155/
https://www.ncbi.nlm.nih.gov/pubmed/36755969
http://dx.doi.org/10.2147/JIR.S392599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900155/
https://www.ncbi.nlm.nih.gov/pubmed/36755969
http://dx.doi.org/10.2147/JIR.S392599

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