SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despite low neutralizing antibody responses

SARS-CoV-2 continues to pose a threat to human health as new variants emerge and thus a diverse vaccine pipeline is needed. We evaluated SARS-CoV-2 HexaPro spike protein formulated in Alhydrogel(®) (aluminium oxyhydroxide) in Syrian hamsters, using an accelerated two dose regimen (given 10 days apar...

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Detalles Bibliográficos
Autores principales: Christensen, Dennis, Polacek, Charlotta, Sheward, Daniel J., Hanke, Leo, McInerney, Gerald, Murrell, Ben, Hartmann, Katrine Top, Jensen, Henrik Elvang, Zimmermann, Julie, Jungersen, Gregers, Illigen, Kristin Engelhart, Isling, Louise Krag, Fernandez-Antunez, Carlota, Ramirez, Santseharay, Bukh, Jens, Pedersen, Gabriel Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900178/
https://www.ncbi.nlm.nih.gov/pubmed/36756130
http://dx.doi.org/10.3389/fimmu.2023.941281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900178/
https://www.ncbi.nlm.nih.gov/pubmed/36756130
http://dx.doi.org/10.3389/fimmu.2023.941281

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