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Phosformer: an explainable transformer model for protein kinase-specific phosphorylation predictions

MOTIVATION: The human genome encodes over 500 distinct protein kinases which regulate nearly all cellular processes by the specific phosphorylation of protein substrates. While advances in mass spectrometry and proteomics studies have identified thousands of phosphorylation sites across species, inf...

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Detalles Bibliográficos
Autores principales: Zhou, Zhongliang, Yeung, Wayland, Gravel, Nathan, Salcedo, Mariah, Soleymani, Saber, Li, Sheng, Kannan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900213/
https://www.ncbi.nlm.nih.gov/pubmed/36692152
http://dx.doi.org/10.1093/bioinformatics/btad046