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GDF11 inhibits adipogenesis of human adipose-derived stromal cells through ALK5/KLF15/β-catenin/PPARγ cascade

Obesity is a metabolic disease characterized by excessive fat storage, and the adipogenic differentiation of adipose-derived stromal cells (ADSCs) is closely linked to its occurrence. Growth differentiation factor 11 (GDF11), a well-known molecule in the field of anti-aging, also has great potential...

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Detalles Bibliográficos
Autores principales: Lin, Shimin, Zhong, Lishan, Chen, Jingyi, Zhao, Zibo, Wang, Rongze, Zhu, Yexuan, Liu, Junwei, Wu, Yanting, Ye, Cuifang, Jin, Fujun, Ren, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900277/
https://www.ncbi.nlm.nih.gov/pubmed/36755591
http://dx.doi.org/10.1016/j.heliyon.2023.e13088