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Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus

Adult neural progenitor cells (aNPCs) ensure lifelong neurogenesis in the mammalian hippocampus. Proper regulation of aNPC fate has thus important implications for brain plasticity and healthy aging. Piwi proteins and the small noncoding RNAs interacting with them (piRNAs) have been proposed to cont...

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Detalles Bibliográficos
Autores principales: Gasperini, Caterina, Tuntevski, Kiril, Beatini, Silvia, Pelizzoli, Roberta, Lo Van, Amanda, Mangoni, Damiano, Cossu, Rosa M, Pascarella, Giovanni, Bianchini, Paolo, Bielefeld, Pascal, Scarpato, Margherita, Pons‐Espinal, Meritxell, Sanges, Remo, Diaspro, Alberto, Fitzsimons, Carlos P, Carninci, Piero, Gustincich, Stefano, De Pietri Tonelli, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900342/
https://www.ncbi.nlm.nih.gov/pubmed/36472244
http://dx.doi.org/10.15252/embr.202153801