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NONO enhances mRNA processing of super‐enhancer‐associated GATA2 and HAND2 genes in neuroblastoma

High‐risk neuroblastoma patients have poor survival rates and require better therapeutic options. High expression of a multifunctional DNA and RNA‐binding protein, NONO, in neuroblastoma is associated with poor patient outcome; however, there is little understanding of the mechanism of NONO‐dependen...

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Detalles Bibliográficos
Autores principales: Zhang, Song, Cooper, Jack AL, Chong, Yee Seng, Naveed, Alina, Mayoh, Chelsea, Jayatilleke, Nisitha, Liu, Tao, Amos, Sebastian, Kobelke, Simon, Marshall, Andrew C, Meers, Oliver, Choi, Yu Suk, Bond, Charles S, Fox, Archa H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900351/
https://www.ncbi.nlm.nih.gov/pubmed/36416237
http://dx.doi.org/10.15252/embr.202254977