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Engineering poly- and micelleplexes for nucleic acid delivery – A reflection on their endosomal escape
For the longest time, the field of nucleic acid delivery has remained skeptical whether or not polycationic drug carrier systems would ever make it into clinical practice. Yet, with the disclosure of patents on polyethyleneimine-based RNA carriers through leading companies in the field of nucleic ac...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Publishers
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900387/ https://www.ncbi.nlm.nih.gov/pubmed/36496051 http://dx.doi.org/10.1016/j.jconrel.2022.12.008 |