Tingible body macrophages arise from lymph node–resident precursors and uptake B cells by dendrites

Antibody affinity maturation depends on the formation of germinal centers (GCs) in lymph nodes. This process generates a massive number of apoptotic B cells, which are removed by a specialized subset of phagocytes, known as tingible body macrophages (TBMs). Although defects in these cells are associ...

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Detalles Bibliográficos
Autores principales: Gurwicz, Neta, Stoler-Barak, Liat, Schwan, Niklas, Bandyopadhyay, Arnab, Meyer-Hermann, Michael, Shulman, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900388/
https://www.ncbi.nlm.nih.gov/pubmed/36705667
http://dx.doi.org/10.1084/jem.20222173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900388/
https://www.ncbi.nlm.nih.gov/pubmed/36705667
http://dx.doi.org/10.1084/jem.20222173

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