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Rate of tau propagation is a heritable disease trait in genetically diverse mouse strains
The speed and scope of cognitive deterioration in Alzheimer's disease is highly associated with the advancement of tau neurofibrillary lesions across brain networks. We tested whether the rate of tau propagation is a heritable disease trait in a large, well-characterized cohort of genetically d...
Autores principales: | Welikovitch, Lindsay A., Dujardin, Simon, Dunn, Amy R., Fernandes, Analiese R., Khasnavis, Anita, Chibnik, Lori B., Kaczorowski, Catherine C., Hyman, Bradley T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900390/ https://www.ncbi.nlm.nih.gov/pubmed/36756365 http://dx.doi.org/10.1016/j.isci.2023.105983 |
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